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Allele : Rho<em1(RHO)Bcgen> rhodopsin; endonuclease-mediated mutation 1, Biocytogen LLC

Primary Identifier  MGI:7506598 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Rho
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Homology directed repair strategy combined with CRISPR/Cas9 technology introduced human RHO genomic fragment that consists of the replacement of mouse exon 1 after the start codon to exon 5 before the stop codon and all introns by the human counterparts. The human rhodopsin is thus expressed under the control of the endogenous mouse promoter.
  • mutations:
  • Insertion
  • synonyms:
  • Rho<hum>,
  • Rho<hum>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories