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Allele : Dicer1<em4Psv> dicer 1, ribonuclease type III; endonuclease-mediated mutation 4, Petr Svoboda

Primary Identifier  MGI:7489654 Allele Type  Endonuclease-mediated
Attribute String  Epitope tag, Modified isoform(s) Gene  Dicer1
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false
molecularNote  Endogenous exons 2-6 and the LTR insertions in intron 6 were deleted, and a construct containing an HA-tag at the N-terminus of the coding sequence and DNA sequence of exon 2 to exon 7 was inserted. This eliminated the expression of a truncated Dicer isoform in mouse oocytes that is dependent on the LTR insertions.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Dicer1<SOM>,
  • Dicer1<SOM>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele