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Allele : Ptgs2<tm1.1Flv> prostaglandin-endoperoxide synthase 2; targeted mutation 1.1, Richard Flavell

Primary Identifier	MGI:7489742	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Ptgs2
Transmission	Germline	Strain of Origin	C57BL/6N
Is Recombinase	false	Is Wild Type	false

molecularNote

Two loxP sites flanking a STOP cassette sequence and a frt-flanked PKG-neomycin cassette were inserted into intron 3. The frt-flanked PKG-neomycin cassette was removed via FLP-mediated recombination in the germline.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
Ptgs2<LSL>,
Ptgs2<LSL>

earliestPublication:
Roulis M, et al. (2020) Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche. Nature 580(7804):524-529

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

4 Publication categories

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