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Allele : Gt(ROSA)26Sor<em2(Aspg)Sjm> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 2, Sean J Morrison

Primary Identifier	MGI:7494115	Allele Type	Endonuclease-mediated
Attribute String	Inserted expressed sequence	Gene	Gt(ROSA)26Sor
Strain of Origin	C57BL/6	Is Recombinase	false
Is Wild Type	false

molecularNote

CRISPR/Cas9 genome editing technology was used to insert a loxp-Stop-loxp sequence followed by a guinea pig asparaginase 1 coding sequence into the Gt(ROSA)26Sor locus.

mutations:
Insertion

synonyms:
Rosa26<LSL-gpASNase1>,
Rosa26<LSL-gpASNase1>

earliestPublication:
Qi L, et al. (2021) Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration. Cell Stem Cell 28(11):1982-1999.e8

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

1 Driven By

3 Publication categories

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