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Allele : Dot1l<tm1.2Saam> DOT1 like histone lysine methyltransferase; targeted mutation 1.2, Scott Armstrong
Primary Identifier  MGI:7511880 Allele Type  Targeted
Attribute String  Null/knockout Gene  Dot1l
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted upstream of exon 5. An FRT-flanked puro cassette with a 3' loxP site was inserted downstream of exon 5. Flp-mediated recombination removed the puro cassette and left exon 5 floxed. Cre-mediated recombination removed exon 5.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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