| Primary Identifier | MGI:7512809 | Allele Type | Endonuclease-mediated |
| Attribute String | Recombinase | Gene | Myh11 |
| Strain of Origin | C57BL/6J x SJL | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | Using CRISPR/Cas9 technology, a a nuclear localization sequence (NLS) followed by a codon optimized Cre recombinase fused to ERT2, a GSG linker and a P2A peptide (for production of a bicistronic mRNA transcript) immediately was inserted into the endogenous Myh11 gene immediately after the first codon ATG in exon 2. Cre expression is constitutive rather than inducible by tamoxifen. |
