Primary Identifier | MGI:7531286 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Alpi |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | An IRES-cre/ERT2 cassette followed by a Frt-flanked neo-selection cassette was inserted into exon 11 of the Alpi gene by homologous recombination in ES cells. Correctly targeted ES cell clones were injected into C57BL/6 blastocysts. Mice were crossed to Flp-expressing mice to delete the neo cassette. |