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Allele : Parp1<tm1.1Shzh> poly (ADP-ribose) polymerase family, member 1; targeted mutation 1.1, Shan Zha
Primary Identifier  MGI:7531481 Allele Type  Targeted
Attribute String  Dominant negative Gene  Parp1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted a FRT neomycin resistance cassette in intron 21 and exon 22 was modified with an A to C point mutation encoding the amino acid substitution of glutamic acid with alanine at position 988 (E988A). Flp-mediated recombination removed the selection cassette.
  • mutations:
  • Single point mutation
  • synonyms:
  • Parp1<A>,
  • Parp1<E988A>,
  • Parp1<E988A>,
  • Parp1<A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

3 Publication categories

Trail: Allele




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