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Allele : Patl2<em1Lwa> protein associated with topoisomerase II homolog 2 (yeast); endonuclease-mediated mutation 1, Lei Wang

Primary Identifier  MGI:7541275 Allele Type  Endonuclease-mediated
Gene  Patl2 Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  Serine codon 279 (AGC) in exon 11 was changed to aspartic acid (GAT) (p.S279D) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation prevents phosphorylation of the residue in the encoded peptide.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Patl2<S279D>,
  • Patl2<S279D>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele