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Allele : Gt(ROSA)26Sor<em1.1(CAG-Casp3)Ddg> gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1.1, David D Ginty
Primary Identifier  MGI:7540317 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Using standard CRISPR-based homologous recombination techniques in embryonic stem (ES) cells, CAG promoter-Frt-Stop-Frt followed by lox-Stop-lox and Casp3 expression cassette were inserted into the Gt(ROSA)26Sor locus. Chimeras were generated by blastocyst injection and subsequent germline transmission was confirmed by tail PCR. The neo-selection cassette was excised using a phiC31 strain.
  • mutations:
  • Insertion
  • synonyms:
  • R26<FSF-LSL-Caspase3>,
  • ROSA26<FSF-LSL-Caspase3>,
  • ROSA26<FSF-LSL-Caspase3>,
  • R26<FSF-LSL-Caspase3>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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