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Allele : Slc25a33<em1(IMPC)J> solute carrier family 25, member 33; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7526370 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Slc25a33
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele from was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GATGCACCCCAGATACCTTG and GCATGAACATCCAGGTGCAG, which resulted in a 501 bp deletion beginning at Chromosome 4 position 149,753,556 bp and ending after 149,754,056 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000184185 (exon 4) and 400 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 104 and early truncation 14 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories