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Allele : Prm1<em1Ssha> protamine 1; endonuclease-mediated mutation 1, Saher Sue Hammoud

Primary Identifier  MGI:7520861 Allele Type  Endonuclease-mediated
Gene  Prm1 Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated an AAA to GCA change resulting in a lusine to alanine substitution at amino acid 49 (p.K49A). A few synonymous alterations were incorporated to introduce an FspI site for genotyping. The K49A mutation results in loss of positive charge as well as loss of acetylation at the site.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • P1<K49A>,
  • P1<K49A>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories