| Primary Identifier | MGI:7522231 | Allele Type | Targeted |
| Attribute String | Inducible, Recombinase | Gene | Fbxo2 |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | The targeting vector was designed to insert a Cre/ERT2 fusion protein into the ATG start codon of the F-box protein 2 (Fbxo2) gene. Specifically, this vector includes (from 5' to 3') a cre/ERT2 fusion gene (Cre recombinase fused to a human estrogen receptor ligand binding domain), a polyadenylation signal, and a loxP-flanked neomycin resistance (neo) cassette. The resulting chimeric mice were bred to a Cre transgenic strain to remove the neo cassette. |
