Primary Identifier | MGI:7514881 | Allele Type | Targeted |
Attribute String | Inducible, Recombinase | Gene | Arr3 |
Transmission | Germline | Strain of Origin | (C57BL/6J x 129S6/SvEvTac)F1 |
Induced With | tamoxifen | Is Recombinase | true |
Is Wild Type | false |
molecularNote | A 2A peptide-CreERT2 and an FRT-flanked neomycin cassette introduced the translation STOP codon (TAG) of the Arr3 gene by homologous recombination in the ES cells. Male chimeras were bred to ACTB-FLPe females for germline transmission and neomycin cassette removal. |