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Allele : Ehd1<tm1b(EUCOMM)Wtsi> EH-domain containing 1; targeted mutation 1b, Wellcome Trust Sanger Institute

Primary Identifier  MGI:7516137 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ehd1
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  The L1L2_Bact_P cassette was inserted at position 6330789 of Chromosome 19 upstream of the critical exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon 2 at position 6331576. The critical exon 2 is thus flanked by loxP sites. Cre-mediated recombination deleted exon 2 and generated a reporter knockout mouse.
  • mutations:
  • Intragenic deletion,
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories