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Allele : Tg(Pgk-tetR,tetO-RNAi:Pum3)#Yuj transgene insertion, John Yu

Primary Identifier  MGI:7516772 Allele Type  Transgenic
Attribute String  Inducible, Knockdown Gene  Tg(Pgk-tetR,tetO-RNAi:Pum3)#Yuj
Is Recombinase  false Is Wild Type  false
molecularNote  A construct containing a Pgk promoter driving a tetracycline repressor gene followed by a poly a sequence and a tetracycline responsive Pol III hybrid promoter driving expression of Pum3 shRNAs. Treatment with doxycycline results in about an 80% reduction in Pum3 mRNA expression in hemizygous embryos.
  • mutations:
  • Insertion
  • synonyms:
  • Puf-A shRNA,
  • Puf-A shRNA
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

3 Publication categories