| Help | About | Contact Us

Allele : Prkdc<m1Yum> protein kinase, DNA activated, catalytic polypeptide; mutation 1, Yumie Takagi

Primary Identifier	MGI:7541571	Allele Type	Spontaneous
Attribute String	Null/knockout	Gene	Prkdc
Strain of Origin	B10.S-H2<s>/SgSlc	Is Recombinase	false
Is Wild Type	false

molecularNote

This spontaneous mutation (TT deletion in exon 57, c.7670_7671del, GRCm39:chr16:g.15587786_15587787del) was found in an inbred B10.S-H2^s/SgSlc colony. The mutation causes a frameshift and premature stop codon (p.F2557Sfs*3).

mutations:
Intragenic deletion

synonyms:
Prkdc<deltaex57>,
Prkdc<deltaex57>

earliestPublication:
Takagi Y, et al. (2023) Characterization of novel, severely immunodeficient Prkdc(Deltaex57/Deltaex57) mice. Biochem Biophys Res Commun 678:193-199

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

2 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76836137

MouseMine