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Allele : Gt(ROSA)26Sor<tm4(tTA,tetO-TREM2*R47H,-EGFP)Gbu> gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Guojun Bu
Primary Identifier  MGI:7541481 Allele Type  Targeted
Attribute String  Conditional ready, Inducible, Inserted expressed sequence, Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted a floxed neomycin stop cassette, tTA, insulator, hCMV*1 promoter with a tetracycline responsive element, intron, human TREM2 with the mutation encoding the amino acid substitution arginine with histidine at position 47 (R47H) plus tagged with 5' HA and 3' triple FLAG tags, IRES, and EGFP reporter gene.
  • mutations:
  • Insertion
  • synonyms:
  • TREM2-R47H,
  • TREM2-R47H
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories





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