|  Help  |  About  |  Contact Us

Allele : Rptor<em2Rjsh> regulatory associated protein of MTOR, complex 1; endonuclease-mediated mutation 2, Reuben J Shaw

Primary Identifier  MGI:7529770 Allele Type  Endonuclease-mediated
Gene  Rptor Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  Serine codon 792 (TCC) in exon 20 was changed to alanine (GCG) (p.S792A) using an sgRNA (targeting CGGCGAGGACTCACCTATGAGGG) and an ssODN template with CRISPR/Cas9 technology. The mutation replaces a phosphorylatable residue in the encoded peptide to a phosphoblocker.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Raptor<A>,
  • Raptor<A>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories