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Allele : Elmo2<tm1.1Jfco> engulfment and cell motility 2; targeted mutation 1.1, Jean-Francois Cote

Primary Identifier  MGI:7544996 Allele Type  Targeted
Gene  Elmo2 Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The targeting construct replaced exon 3 with one containing the mutation responsible for the amino acid substitution of leucine to alanine at position 43 (L43A). This mutation abolishes the function of the RAS-Binding domain. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Elmo2<RBD>,
  • Elmo2<RBD>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories