|  Help  |  About  |  Contact Us

Allele : Elac2<em1Afi> elaC ribonuclease Z 2; endonuclease-mediated mutation 1, Aleksandra Filipovska

Primary Identifier  MGI:7545038 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Elac2
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  Alanine codon 537 (GCT) in exon 17 was changed to threonine (ACT) (p.A537T) using an sgRNA and an ssODN template with CRISPR/Cas9. The mutation is the equivalent of the human p.A541T mutation associated with prostate cancer predisposition.
  • mutations:
  • Single point mutation
  • synonyms:
  • ELAC2 A537T,
  • ELAC2 A537T
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories