| Primary Identifier | MGI:7548868 | Allele Type | Targeted |
| Attribute String | Conditional ready | Gene | Col1a1 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site and a mini-cDNA representing exons 47-51 through to the poly(A) signal sequence, followed by an FRT site flanked neomycin resistance gene cassette and a second loxP site, were inserted into intron 46. Proline codon 1153 (CCC) in the endogenous exon 47 was changed to alanine (GCC) (p.P1153A). Only after Cre-mediated removal of the inserted wildtype sequence will this allele express the mutated version. |
