| Primary Identifier | MGI:7545684 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Arl14ep |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TTAGTTAAACCTGAAAGCCA and AAACTGCATTCCAGACTCGG, which resulted in a 475 bp deletion beginning at Chromosome 2 position 106,966,958 bp and ending after 106,967,432 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001208985 (exon 3) and 347 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 141 and early truncation 7 amino acids later. |
