| Primary Identifier | MGI:7548521 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Zp2 |
| Strain of Origin | (C57BL/6 x DBA/2)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a CT to TG substitution (c.1622-1623CT>TG) resulting in a threonine to methionine change at amino acid 541 (p.T541M) in exon 14. A c.1632G>A synonymous mutation was also introduced. This corresponds to the p.Thr539Met mutation identified in a human female with primary infertility. |
