| Primary Identifier | MGI:7548761 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Scn5a |
| Transmission | Germline | Strain of Origin | C57BL/6NTac |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A G to A change at position 674 (c.674G>A) resulting in an arginine to glutamine substitution at amino acid 225 (p.R225Q) was introduced in exon 6 and a loxP-flanked neomycin cassette was inserted downstream of exon 6. This is a novel non-synonymous variant associated with idiopathic dilated cardiomyopathy in human located in the S4 segment domain I (DI-S4). |
