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Allele : Prkd2<em1Btlr> protein kinase D2; endonuclease-mediated mutation 1, Bruce Beutler

Primary Identifier  MGI:7549275 Allele Type  Endonuclease-mediated
Gene  Prkd2 Inheritance Mode  Semidominant
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Tryptophan codon 807 (TGG) in exon 17 was changed to arginine (AGG) (p.W807R) using an sgRNA (targeting TCTCAGCCACCCATGGTTAC) and an ssODN template with CRISPR/Cas9 technology. The mutation recapitulates the ENU-induced Purnama allele.
  • mutations:
  • Single point mutation
  • synonyms:
  • Prkd2<W807R>,
  • Prkd2<W807R>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele