| Primary Identifier | MGI:7549174 | Allele Type | Chemically induced (ENU) |
| Gene | Map4k4 | Inheritance Mode | Recessive |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | ENU mutagenesis induced an undefined point mutation at GRCm38:chr1:40004864 that causes a missense mutation at glutamine codon (Q) 687 (CAG) (in ENSMUSP00000126961 and ENSMUSP00000141400; different coordinates in other isoforms) to either lysine (AAG) or glutamine (GAG). The mutation is implicated in altered T cell-dependent antibody responses to immunization. |
