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Allele : Fasn<tm1.1Mmats> fatty acid synthase; targeted mutation 1.1, Michihiro Matsumoto

Primary Identifier	MGI:7549097	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Fasn
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

A loxP-flanked neomycin cassette was inserted upstream of exon 4 and third loxP site was inserted downstream of exon 10. The neomycin cassette was removed via cre-mediated recombination leaving exons 4-10 floxed.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
F,
F

earliestPublication:
Matsukawa T, et al. (2023) Hepatic FASN deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models. JCI Insight 8(17)

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

3 Publication categories

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