| Primary Identifier | MGI:7567435 | Allele Type | Targeted |
| Attribute String | Conditional ready, Hypomorph | Gene | Mir501 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The coding sequence was inverted and flanked with a pair of loxP sites and a pair of lox2722 sites via homologous recombination. Decreased expression in hemizygous and homozygous mice was confirmed by qRT-PCR. Expression of Clnc5 or the four nearby miRNAs was not reduced. Cre-mediated recombination will invert the coding sequence and restore expression. |
