Primary Identifier | MGI:7620070 | Allele Type | Endonuclease-mediated |
Attribute String | Conditional ready, Humanized sequence, Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology inserted a CAG promoter, loxP-flanked Stop cassette (LSL), human MUC15 coding sequence, P2A, tdTomato and WPRE into the locus. This creates a conditional-ready allele that will express the human gene only after cre-mediated excision of the STOP cassette. |