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Allele : Bcl2l1<tm1.1Jusa> BCL2-like 1; targeted mutation 1.1, Junichi Sadoshima

Primary Identifier  MGI:7550776 Allele Type  Targeted
Gene  Bcl2l1 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Serine codon 14 (TCC) in exon 2 was changed to alanine (GCC) (p.S14A) and a loxP site flanked neomycin resistance gene cassette was inserted into intron 2. The neo cassette was removed through subsequent Cre-mediated recombination. The mutation prevents phosphorylation of the affected residue in the encoded peptide.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • Bcl-xL S14A KI,
  • Bcl-xL S14A KI
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele