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Allele : Sting1<tm1.1Ccah> stimulator of interferon response cGAMP interactor 1; targeted mutation 1.1, Chih-Chi Andrew Hu
Primary Identifier  MGI:7565684 Allele Type  Targeted
Attribute String  Constitutively active Gene  Sting1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  Valine codon 154 (GTT) in exon 5 was changed to methionine (ATG) (p.V154M) and an FRT site flanked neomycin resistance gene cassette was inserted into intron 5. The neo cassette was removed through subsequent Flp-mediated recombination. The mutation renders the encoded peptide constitutively active.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • STING V154M,
  • STING V154M
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories





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