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Allele : Stat3<em1Jyue> signal transducer and activator of transcription 3; endonuclease-mediated mutation 1, Jicheng Yue
Primary Identifier  MGI:7562330 Allele Type  Endonuclease-mediated
Gene  Stat3 Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a threonine to glutamic acid substitution at amino acid 716 (pT716E). Transcriptional activity of Stat3 is significantly reduced.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Stat3<T716E>,
  • Stat3<T716E>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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0 Driven By

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