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Allele : Malt1<em2Krad> MALT1 paracaspase; endonuclease-mediated mutation 2, Daniel Krappmann

Primary Identifier  MGI:7571554 Allele Type  Endonuclease-mediated
Gene  Malt1 Strain of Origin  (C57BL/6N x 129-Malt1<em1Krad>)F1
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated the paracaspase mutation, a TGT to GCG change resulting in a cysteine to alanine change at amino acid 472 (p.C472A) in exon 11, in zygotes carrying the Malt1em1Krad allele. These mice thus carry the p.C472A mutation as well as p.E324A, p.E814A, and p.E803A.
  • mutations:
  • Single point mutation
  • synonyms:
  • Malt1<TBMPM>,
  • Malt1<TBMPM>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories