Primary Identifier | MGI:7575978 | Allele Type | Targeted |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Asxl3 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 5 was replaced with the mouse 5' end of exon 5 including the ATG codon, human ASXL3 cDNA containing a C to G change at position 2168 (c.2168C>G) resulting in a proline to arginine substitution at amino acid 723 (p.P723R) and an FRT-flanked neomycin resistance gene. The neomycin resistance gene was removed via flp-mediated recombination. |