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Allele : Fcgr3<em1(FCGR2A)Synbl> Fc receptor, IgG, low affinity III; endonuclease-mediated mutation 1, Synbal

Primary Identifier  MGI:7607011 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence, Inserted expressed sequence, Null/knockout Gene  Fcgr3
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  Using a CRISPR/Cas9 approach, an ‘active genetic cassette’ (AGC) was used to remove the endogenous mouse gene coding region and replace it with a functional human coding region under the control of the endogenous mouse promoter.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Humanized Mouse-hFcgr3,
  • Humanized Mouse-hFcgr3
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

2 Publication categories