|  Help  |  About  |  Contact Us

Allele : Tgfbr1<em1Yixi> transforming growth factor, beta receptor I; endonuclease-mediated mutation 1, Yichuan Xiao

Primary Identifier  MGI:7576933 Allele Type  Endonuclease-mediated
Gene  Tgfbr1 Is Recombinase  false
Is Wild Type  false
molecularNote  Lysine codon 268 (AAA) in exon 4 was changed to arginine (AGA) (p.K268R) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation blocks ubiquitination of the residue in the encoded peptide.
  • mutations:
  • Single point mutation
  • synonyms:
  • Tgfbr1<K268R>,
  • Tgfbr1<K268R>
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories