| Primary Identifier | MGI:7576952 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Crx |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Glutamic acid codon 80 (GAG) in exon 3 was changed to alanine (GCG) (p.E80A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation, in the homeodomain (HD) of the encoded peptide, is the equivalent of the same human mutation associated with dominant cone-rod dystrophy 2 (CRD2). |
