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Allele : Cacna1a<em1Lutzy> calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; endonuclease-mediated mutation 1, Cathy Lutz

Primary Identifier	MGI:7577429	Allele Type	Endonuclease-mediated
Attribute String	Humanized sequence	Gene	Cacna1a
Strain of Origin	C57BL/6J	Is Recombinase	false
Is Wild Type	false

molecularNote

Using CRISPR/cas9 endonuclease-mediated genome editing, the missense S220L (TCA to CTG, serine to leucine) variant was introduced in the exon 5 of the Cacna1a gene.

mutations:
Nucleotide substitutions

synonyms:
Cacna1a<S220L>,
Cacna1a<S220L>

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

2 Publication categories

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