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Allele : Ints15<em1Takas> integrator complex subunit 15; endonuclease-mediated mutation 1, Shuji Takada

Primary Identifier  MGI:7578876 Allele Type  Endonuclease-mediated
Attribute String  Modified isoform(s), Null/knockout Gene  Ints15
Strain of Origin  (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing technology was used to generate a deletion in exon 6 (corresponding to the last exon). The exon 6 disruption is considered analogous to the INTS15 exon 6 missense mutation found in human patients with variable panocular malformations (VPM)
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Ints15<exon6>,
  • Ints15<exon6>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories