Primary Identifier | MGI:7578876 | Allele Type | Endonuclease-mediated |
Attribute String | Modified isoform(s), Null/knockout | Gene | Ints15 |
Strain of Origin | (C57BL/6 x DBA/2)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 genome editing technology was used to generate a deletion in exon 6 (corresponding to the last exon). The exon 6 disruption is considered analogous to the INTS15 exon 6 missense mutation found in human patients with variable panocular malformations (VPM) |