Primary Identifier | MGI:7579215 | Allele Type | Endonuclease-mediated |
Attribute String | Inserted expressed sequence | Gene | Ts(17<16>;EIF1AX-Xist)67Jlaw |
Transmission | Germline | Strain of Origin | B6EiC3Sn a/A-Ts(17<16>)65Dn/J |
Is Recombinase | false | Is Wild Type | false |
description | ES cell derived from B6EiC3Sn a/A-Ts(17<16>)65Dn/J line. |
molecularNote | Using CRISPR/Cas9 technology, the mouse Xist gene, driven by human eukaryotic translation initiation factor 1A X-linked (EIF1AX) promoter was inserted downstream of the Runx1 locus on chromosome 16 (a low-gene density region designated as Igs50) of the trisomy chromosome 16 in the host ES cell derived from B6EiC3Sn a/A-Ts(17<16>)65Dn/J line. |