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Allele : Ts(17<16>;EIF1AX-Xist)67Jlaw trisomy, Chr 16 translocation to Chr 17, Jeanne Lawrence 67

Primary Identifier  MGI:7579215 Allele Type  Endonuclease-mediated
Attribute String  Inserted expressed sequence Gene  Ts(17<16>;EIF1AX-Xist)67Jlaw
Transmission  Germline Strain of Origin  B6EiC3Sn a/A-Ts(17<16>)65Dn/J
Is Recombinase  false Is Wild Type  false
description  ES cell derived from B6EiC3Sn a/A-Ts(17<16>)65Dn/J line.
molecularNote  Using CRISPR/Cas9 technology, the mouse Xist gene, driven by human eukaryotic translation initiation factor 1A X-linked (EIF1AX) promoter was inserted downstream of the Runx1 locus on chromosome 16 (a low-gene density region designated as Igs50) of the trisomy chromosome 16 in the host ES cell derived from B6EiC3Sn a/A-Ts(17<16>)65Dn/J line.
  • mutations:
  • Translocation,
  • Insertion
  • synonyms:
  • Igs50<em1(EIF1AX-Xist)Jlaw>,
  • Igs50<em1(EIF1AX-Xist)Jlaw>,
  • Ts65DN-Xist,
  • Ts65DN-Xist
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

1 Driven By

3 Publication categories