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Allele : Pax6<em8(PAX6*R240X)Ems> paired box 6; endonuclease-mediated mutation 8, Elizabeth M Simpson

Primary Identifier  MGI:7579265 Allele Type  Endonuclease-mediated
Attribute String  Epitope tag, Humanized sequence, Inserted expressed sequence Gene  Pax6
Strain of Origin  B6.Cg-Pax6<Sey>/EmsMmmh Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-targeting of zygotes carrying Pax6em3Ems allele harbors a triple FLAG tag at the ATG translation initiation sequence in exon 4 was used to replace mouse exon 9 with human exon 9 sequence that contains the human mutation (c.718C>T (p.Arg240Ter)).
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Pax6<FHe9->,
  • Pax6<em8(FLAG/PAX6*R240X)Ems>,
  • Pax6<em8(FLAG/PAX6*R240X)Ems>,
  • Pax6<FHe9->
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

2 Publication categories