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Allele : Mdfic<em1Nlh> MyoD family inhibitor domain containing; endonuclease-mediated mutation 1, Natasha L Harvey

Primary Identifier  MGI:7638754 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Mdfic
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology targeting the region between c.379G and c.396C generated deletion alleles. This allele contains a 2 bp deletion this region resulting in a frameshift and premature stop codon. This mimics the common mutation in humans c.391dup (p.Met131Asnfs*3).
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Mdfic<M131fs*>,
  • Mdfic<M131fs*>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

2 Publication categories