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Allele : Col1a1<tm1(tetO-PHGDH)Mgvh> collagen, type I, alpha 1; targeted mutation 1, Matthew G Vander Heiden
Primary Identifier  MGI:7610185 Allele Type  Targeted
Attribute String  Inserted expressed sequence, RMCE-ready Gene  Col1a1
Transmission  Germline Strain of Origin  (C57BL/6 x 129S4/SvJae)F1
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting vector was designed to insert a human PHGDH cDNA placed downstream of a tetracycline-responsive element (TRE) promoter, and targeted via recombinase-mediated cassette exchange (RMCE) into the ubiquitously expressed collagen, type I, alpha 1 (Col1a1) gene. The targeting vector also contained a hygromycin resistance cassette.
  • mutations:
  • Insertion
  • synonyms:
  • PHGDH<tetO>,
  • PHGDH<tetO>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories





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