Primary Identifier | MGI:7581999 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Del(14Gjb6-Cryl1)1Lmon |
Strain of Origin | C57BL/6JOlaHsd | Is Recombinase | false |
Is Wild Type | false |
description | The expression of the Gjb2 gene, located proximally to the deletion, is nearly abolished in all cochlear structures. |
molecularNote | Deletion that spans 274,050 bp of mouse chromosome 14, from Gjb6 exon3 to Cryl1 exon 1, engineered by CRISPR-Cas9. |