| Help | About | Contact Us

Allele : Cdkl5<tm1.1Arikk> cyclin dependent kinase like 5; targeted mutation 1.1, Jyothi Arikkath

Primary Identifier	MGI:7587841	Allele Type	Targeted
Attribute String	Conditional ready	Gene	Cdkl5
Transmission	Germline	Strain of Origin	C57BL/6NTac
Is Recombinase	false	Is Wild Type	false

molecularNote

A LoxP site was inserted in intron 3 and a Frt-Neo-Frt-LoxP cassette was inserted in intron 4. Flp-mediated recombination in the germline resulted in the removal of the promoter-driven neomycin selection cassette.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
CDKL5 Flox,
CDKL5 Flox

earliestPublication:
Schroeder E, et al. (2019) Neuron-Type Specific Loss of CDKL5 Leads to Alterations in mTOR Signaling and Synaptic Markers. Mol Neurobiol 56(6):4151-4162

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

0 Driven By

4 Publication categories

Questions? Comments? Click here!

MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Your name:
Your email address:
Subject:
Message:	---- Current page: ---- /mousemine/report.do?id=76869361

MouseMine