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Allele : Ap2a2<tm1.1Momk> adaptor-related protein complex 2, alpha 2 subunit; targeted mutation 1.1, Magdalene K Montgomery

Primary Identifier  MGI:7612025 Allele Type  Targeted
Attribute String  Conditional ready Gene  Ap2a2
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
molecularNote  The L1L2_Bact_P cassette was inserted at position 141178192 of Chromosome 7 upstream of the exon 4 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the exon 4 at position 141179040. Exon 4 is thus flanked by loxP sites. A "conditional ready" (floxed) allele was created by flp mediated recombination. Subsequent cre expression results in a knockout mouse.
  • mutations:
  • Insertion
  • synonyms:
  • Ap2a2<fl>,
  • Ap2a2<fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories