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Allele : Tg(CMV-IL2/IL15)1-1Jic transgene insertion 1-1, Central Institute for Experimental Animals, Japan

Primary Identifier	MGI:7623211	Allele Type	Transgenic
Attribute String	Inserted expressed sequence	Gene	Tg(CMV-IL2/IL15)1-1Jic
Strain of Origin	NOD.129-Il2rg<tm1Sug>	Is Recombinase	false
Is Wild Type	false

molecularNote

Under the control of a CMV promoter, this transgene expresses a human IL-15 cDNA, whose signal peptide sequence was replaced with that of the human IL-2 gene for improving secretion.

mutations:
Insertion

synonyms:
Tg(CMV-IL15)1Jic,
Tg(CMV-IL15)1Jic

earliestPublication:
Katano I, et al. (2017) Long-term maintenance of peripheral blood derived human NK cells in a novel human IL-15- transgenic NOG mouse. Sci Rep 7(1):17230

1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

1 Carried By

1 Driven By

4 Publication categories

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