| Primary Identifier | MGI:7611910 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Copg1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Lysine codon 652 (AAA) in exon 19 was changed to glutamic acid (GAA) (c.1954A>G:p.K652E) using an sgRNA and an ssODN template with CRISPR/Cas9. The mutation, in the appendage domain of the encoded peptide, is the equivalent of the same human mutation associated with combined immunodeficiency (CID). |
