| Primary Identifier | MGI:7614463 | Allele Type | Endonuclease-mediated |
| Gene | Trim24 | Strain of Origin | C57BL/6J |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Cysteine codons 52 (TGC) and 55 (TGC) in exon 1 were changed to alanine (GCA) (p.C52A, p.C55A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutations, in the RING E3-ligase domain of the encoded peptide, render the peptide ligase-dead. |
